On April 28, 2026, HLN released a new version of the Immunization Calculation Engine (ICE) with updates to Hepatitis B and Polio clinical logic. ICE is a state-of-the-art, open source software system that provides clinical decision support for immunizations across Immunization Information Systems (IIS), Electronic Health Record (EHR), and Personal Health Record (PHR) systems.
What’s New in ICE:
- Hepatitis B: Transitioned from a 3-dose Newborn Series and 3-dose Child/Adolescent Series to a modified 3-dose Child/Adolescent Series. Added support for a new 4-dose Child/Adolescent Series.
- Polio: Added support for CVX 324 Poliovirus, inactivated, fractional-dose (fIPV) and added support for a new Polio fIPV Series. Updated handling of OPV vaccines to consider CVX 178 and CVX 179 as inadvertent and consider CVX 182 as inadvertent if administered on or after 4/1/2016.
The ICE Implementation Guide and ICE Implementation Guide Codes sheet have been updated to reflect these changes, including the new Hep B 4-dose series, removal of the Hep B 3-dose Newborn Series, the new CVX 324 code, and the new Polio fIPV Series.
Please see the release notes for additional details. Try ICE with the CDS Insight testing platform and download ICE v2.56.1 today. Questions? See our wiki or reach out to the ICE team at ice@hln.com.