On August 18, 2026, HLN released a new version of the open-source Immunization Calculation Engine (ICE) software with clinical logic refinements and expanded configuration and output options.
What’s New in ICE?
Clinical logic updates
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DTP:
- Updated the DTP component of several combination vaccines to better reflect the component composition.
- Refined primary series exception logic, including specification of Tdap when the adolescent Tdap dose has not been fulfilled and adjustments to select evaluation and forecasting intervals.
- Updated the “Six by Seven Rule” logic to account for a 7-year minimum age and count only shots administered on distinct dates.
- Refined handling of DT based on date administered.
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Meningococcal B:
- Added supplemental clinical messaging related to risk- and shared clinical decision-making indications.
- Updated the forecast for patients who are complete to convey messaging regarding booster vaccination for high-risk patients.
- Added support for CVX 164 (MenB unspecified) as a potential final dose in MenB series.
- Enabled a 2-dose completion pathway in the MenB FHbp 3-Dose Series and the MenB 4C 3-Dose Series.
- https://cdsframework.atlassian.net/wiki/spaces/ICE/pages/14352501/Pneumococcal+Vaccine+Group
- Pneumococcal: Refined clinical messaging to remove references to PCV13.
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Zoster:
- Improved support for CVX 121 (Zoster vaccine, live).
- Added support for a new Zoster 3-dose Series, with historically appropriate CVX 121 considered as a (potential) Valid dose for target dose 1.
- Updated the Zoster 2-dose Series: Added support for grace period on dose 1 absolute minimum age. Added support for CVX 188 (Zoster vaccine, unspecified) as a (potential) Valid CVX Code for the final dose.
Configuration option
- Hepatitis B and Polio: Introduced a new installation configuration option to give users greater flexibility in setting the evaluation of off-schedule extra shots in the Hep B 3-dose Child/Adolescent Series and the polio series. When the configuration option is enabled, ICE will evaluate the extra shot as Accepted rather than Valid.
Schedule authority output
- Added an optional feature to return the associated vaccine group schedule authority or authorities in forecasts, as indicated on the Clinical Guidelines page.
See the latest logic updates in action using CDS Insight, a free tool that allows users to interact with HLN Consulting’s locally-hosted instance of the latest version of ICE. Simulate patient scenarios and receive immunization evaluations and recommendations based on the latest ICE rules.
Please see the Release Notes for additional details and download ICE v2.58.1 today.
Questions? Please reach out to the ICE team at ice@hln.com.