Clinical Decision Support (CDS)

HLN released ICE v2.55.1 with updated clinical logic for Hepatitis A, Hepatitis B, Polio, and COVID-19 vaccines, plus faster performance and improved deployment flexibility. HLN is also excited to announce CDS Insight, a new interactive platform for testing ICE logic in real time. Register for a free account today.

HLN has released a new version of the open source Immunization Calculation Engine (ICE) software, adding support for four additional vaccine groups: cholera, Japanese encephalitis, typhoid, and yellow fever. The ICE default immunization schedule now supports immunization evaluation and forecasting across 22 vaccine groups.

Federal policy shifts put clinical decision support and the open-source Immunization Calculation Engine at the center of a vital question: How can we help users navigate a fractured landscape?

HLN has released an updated version of the open-source Immunization Calculation Engine (ICE) with support for revised COVID-19 vaccine recommendations and core technical enhancements. The release includes updated seasonal COVID-19 logic for pediatric patients and infrastructure improvements to simplify deployment for IIS and EHR implementers.

The open-source Immunization Calculation Engine (ICE) evaluation and forecasting software will continue to support the hepatitis B birth dose and hepatitis B series completion, in line with the evidence base supporting these recommendations.

HLN has released a new version of the open-source Immunization Calculation Engine (ICE) software, with key updates for COVID-19, mpox, and technical upgrades. This release adds support for evidence-based COVID-19 recommendations for the 2025-2026 season, in line with recommendations from the American Academy of Pediatrics and the American Academy of Family Physicians. Additionally, this release updates support for mpox vaccines and updates the ICE service to Java 21.

HLN reaffirms its commitment to evidence-based immunization recommendations in the Immunization Calculation Engine (ICE) open source software. With input from the ICE Advisory Group, ICE will align with guidance from professional medical societies like AAP, AAFP, ACOG, and ACP to ensure accurate, trusted vaccine evaluation and forecasting.

The Immunization Calculation Engine (ICE) Advisory Group convened on September 29, 2025, with over 30 experts across public health, healthcare, and health IT. Discussion centered on immunization decision support guidelines, including ACIP versus alternative evidence-based sources, and the operational and technical challenges created by a shifting immunization landscape.