Immunization Calculation Engine (ICE)

HLN has released an updated version of the open-source Immunization Calculation Engine (ICE) with support for revised COVID-19 vaccine recommendations and core technical enhancements. The release includes updated seasonal COVID-19 logic for pediatric patients and infrastructure improvements to simplify deployment for IIS and EHR implementers.

The open-source Immunization Calculation Engine (ICE) evaluation and forecasting software will continue to support the hepatitis B birth dose and hepatitis B series completion, in line with the evidence base supporting these recommendations.

HLN has released a new version of the open-source Immunization Calculation Engine (ICE) software, with key updates for COVID-19, mpox, and technical upgrades. This release adds support for evidence-based COVID-19 recommendations for the 2025-2026 season, in line with recommendations from the American Academy of Pediatrics and the American Academy of Family Physicians. Additionally, this release updates support for mpox vaccines and updates the ICE service to Java 21.

HLN reaffirms its commitment to evidence-based immunization recommendations in the Immunization Calculation Engine (ICE) open source software. With input from the ICE Advisory Group, ICE will align with guidance from professional medical societies like AAP, AAFP, ACOG, and ACP to ensure accurate, trusted vaccine evaluation and forecasting.

The Immunization Calculation Engine (ICE) Advisory Group convened on September 29, 2025, with over 30 experts across public health, healthcare, and health IT. Discussion centered on immunization decision support guidelines, including ACIP versus alternative evidence-based sources, and the operational and technical challenges created by a shifting immunization landscape.

HLN Consulting is launching the Immunization Calculation Engine (ICE) Advisory Group to ensure its open-source immunization decision support software keeps pace with evolving vaccine recommendations. The group brings together public health, IIS, EHR, and provider leaders to guide ICE’s clinical alignment, clarify complex recommendations, and share implementation feedback.

HLN has released ICE version 2.48.1 with key updates for influenza and RSV vaccines. This release adds support for new CVX codes, including the self/caregiver-administered influenza vaccine and the new clesrovimab monoclonal antibody product for prevention of infant RSV. Additionally, this release supports the expanded risk-based recommendation for adult RSV in alignment with the latest immunization recommendations.

Immunization guidelines are starting to diverge, with the CDC and AAP issuing conflicting COVID-19 recommendations for children. This blog explores what this split might mean for public health, clinical decision support, and the future of the open-source Immunization Calculation Engine (ICE).