Immunization Calculation Engine (ICE)

CMS Immunization Measures Updates to the 2026 Child and Adult Core Sets

BY Marcey Propp and Lilly Kan ON February 25, 2026 Immunization Information System (IIS) | Clinical Decision Support (CDS) | Immunization Calculation Engine (ICE) | Public Health

Recent changes by the Centers for Medicare & Medicaid Services (CMS) in immunization quality measures in the Child and Adult Core Sets fundamentally jeopardize the outlook for vaccine equity and mark a pivotal moment for public health. Read why a jurisdiction’s Immunization Information System (IIS) is now a more vital asset in data-driven vaccine decision making.

HLN Adds New Vaccine Groups to the Open Source Immunization Calculation Engine Forecaster

HLN has released a new version of the open source Immunization Calculation Engine (ICE) software, adding support for four additional vaccine groups: cholera, Japanese encephalitis, typhoid, and yellow fever. The ICE default immunization schedule now supports immunization evaluation and forecasting across 22 vaccine groups.

Federal Immunization Policy Changes and Their Impact on the ICE Forecaster

Federal policy shifts put clinical decision support and the open-source Immunization Calculation Engine at the center of a vital question: How can we help users navigate a fractured landscape?

HLN Releases ICE with Support for Updated COVID-19 Vaccine Recommendations and Core Technical Enhancements

HLN has released an updated version of the open-source Immunization Calculation Engine (ICE) with support for revised COVID-19 vaccine recommendations and core technical enhancements. The release includes updated seasonal COVID-19 logic for pediatric patients and infrastructure improvements to simplify deployment for IIS and EHR implementers.

Reflecting on the AIM 2025 Leadership in Action Conference

BY Marcey Propp ON December 19, 2025 Immunization Information System (IIS) | Events | Immunization Calculation Engine (ICE) | Public Health

Reflections from the AIM 2025 Leadership in Action Conference provide an opportunity to celebrate the milestones and successes immunization program managers, staff and partners achieved together this year and look ahead to 2026!

Immunization Calculation Engine (ICE) to Continue Support for the Hepatitis B Birth Dose and Series Completion

The open-source Immunization Calculation Engine (ICE) evaluation and forecasting software will continue to support the hepatitis B birth dose and hepatitis B series completion, in line with the evidence base supporting these recommendations.

ICE Adds Support for Evidence-Based COVID-19 Recommendations

HLN has released a new version of the open-source Immunization Calculation Engine (ICE) software, with key updates for COVID-19, mpox, and technical upgrades. This release adds support for evidence-based COVID-19 recommendations for the 2025-2026 season, in line with recommendations from the American Academy of Pediatrics and the American Academy of Family Physicians. Additionally, this release updates support for mpox vaccines and updates the ICE service to Java 21.

Public health, decision support, and AI took center stage at HL7’s latest workgroup meeting

HLN participated in HL7’s 40th FHIR Connectathon and 39th Annual Plenary in Pittsburgh, engaging in public health, clinical decision support, and interoperability discussions. From FHIR Query & Response use cases to thought-provoking AI plenary sessions, HLN shared insights and shared its work in immunization forecasting and electronic case reporting.

HLN Re-Affirms Commitment to Evidence-based Recommendations in Immunization Calculation Engine (ICE)

HLN reaffirms its commitment to evidence-based immunization recommendations in the Immunization Calculation Engine (ICE) open source software. With input from the ICE Advisory Group, ICE will align with guidance from professional medical societies like AAP, AAFP, ACOG, and ACP to ensure accurate, trusted vaccine evaluation and forecasting.

Immunization Calculation Engine Advisory Group Convenes Diverse Stakeholders

The Immunization Calculation Engine (ICE) Advisory Group convened on September 29, 2025, with over 30 experts across public health, healthcare, and health IT. Discussion centered on immunization decision support guidelines, including ACIP versus alternative evidence-based sources, and the operational and technical challenges created by a shifting immunization landscape.